Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752748 | 0.90 | FASN (0.55) | FASNCYP3A4MEN1KMT2AHPGD | |
| SCHEMBL30550358 | 0.84 | FASN (0.48) | FASNCYP3A4MEN1KMT2APOLB | |
| SCHEMBL25381773 | 0.77 | FASN (0.61) | FASNCYP3A4MEN1KMT2AHPGD | |
| SCHEMBL154937 | 0.76 | FASN (1.00) | FASNCYP3A4MEN1KMT2APOLB | |
| SCHEMBL29929654 | 0.76 | FASN (1.00) | FASNCYP3A4MEN1KMT2APOLB | |
| SCHEMBL4727216 | 0.76 | CYP2D6 (0.57) | FASNCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL9752929 | 0.75 | HMGCR (0.50) | CYP3A4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7837299 | 0.73 | ALDH1A1 (0.61) | FASNCYP3A4MEN1KMT2AKDM4E | |
| SCHEMBL17301627 | 0.72 | FASN (0.55) | FASNCYP3A4MEN1KMT2AMAPT | |
| SCHEMBL18801124 | 0.71 | CYP3A4 (0.58) | CYP3A4MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028933-A1 | DRYOPTERIS FRAGRANS PHLOROGLUCINOL COMPOUND FLAVASPIDIC ACID BB AND ANTIBACTERIAL APPLICATION THEREOF | 广东药科大学 | 2019-02-14 | — | — | WO | disclosed |
| EP-2606176-B1 | THERMAL TREATMENT | UNIV ASTON (GB) | 2014-10-08 | — | — | EP | disclosed |
| US-20130118886-A1 | Thermal Treatment | ASTON UNIVERSITY (GB) | 2013-05-16 | — | — | US | disclosed |