Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935993 | 0.90 | FASN (0.61) | FASNMEN1KMT2APAK1HMGCR | |
| SCHEMBL9752929 | 0.85 | HMGCR (0.50) | MEN1KMT2AHMGCRALDH1A1KDM4E | |
| SCHEMBL4727216 | 0.81 | CYP2D6 (0.57) | FASNMEN1KMT2APAK1ALDH1A1 | |
| SCHEMBL7837299 | 0.78 | ALDH1A1 (0.61) | FASNMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17301627 | 0.77 | FASN (0.55) | FASNMEN1KMT2APAK1HMGCR | |
| SCHEMBL30550358 | 0.77 | FASN (0.48) | FASNMEN1KMT2APAK1HMGCR | |
| SCHEMBL27997509 | 0.76 | HMGCR (0.57) | FASNMEN1KMT2AHMGCRALDH1A1 | |
| SCHEMBL17114454 | 0.76 | CA12 (0.57) | FASNTSHR | |
| SCHEMBL24169601 | 0.75 | FASN (0.49) | FASNMEN1KMT2APAK1HMGCR | |
| SCHEMBL17305080 | 0.75 | FASN (0.52) | FASNMEN1KMT2APAK1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009595-A1 | ANTI-VIRAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |