Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493731 | 0.81 | POLB (0.60) | SMN1; SMN2POLBHPGDRAB9AHTT | |
| SCHEMBL10932120 | 0.74 | STAT3 (0.61) | POLBHPGDRAB9AHTTALDH1A1 | |
| SCHEMBL27810403 | 0.74 | STAT3 (0.50) | GAASMN1; SMN2POLBALDH1A1CA12 | |
| SCHEMBL3965227 | 0.74 | STAT3 (0.47) | HTTALDH1A1CA12CA1CA2 | |
| SCHEMBL7412504 | 0.73 | GAA (0.57) | GAASMN1; SMN2POLBHPGDRAB9A | |
| SCHEMBL27765152 | 0.73 | POLB (0.51) | SMN1; SMN2POLBHPGDRAB9AHTT | |
| SCHEMBL8066357 | 0.72 | GAA (0.59) | GAASMN1; SMN2POLBHPGDRAB9A | |
| SCHEMBL9243189 | 0.71 | ALOX15 (0.47) | SMN1; SMN2POLBALDH1A1STAT3 | |
| SCHEMBL9243186 | 0.70 | ENPP3 (0.43) | SMN1; SMN2HPGDALDH1A1MAPTSTAT3 | |
| SCHEMBL28659206 | 0.70 | ALOX15 (0.45) | SMN1; SMN2POLBALDH1A1MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915427-B2 | Process for producing aminoacetyl pyrrolidine carbonitrile derivative and intermediate for production thereof | KYORIN PHARMACEUTICALS CO., LTD. (JP) | 2011-03-29 | — | — | US | disclosed |
| US-20090048454-A1 | Process for Producing Aminoacetyl Pyrrolidine Carbonitrile Derivative and Intermediate for Production Thereof | KYORIN PHARMACEUTICALS CO., LTD. (JP) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048454-A1 | Process for Producing Aminoacetyl Pyrrolidine Carbonitrile Derivative and Intermediate for Production Thereof | CBR3, CPS1, CBR1 | GAA 3647/4885SMN1; SMN2 3794/4885POLB 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.