Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938473 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL14938440 | 0.88 | RAB9A (0.63) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL14938438 | 0.88 | RAB9A (0.63) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL14938482 | 0.86 | ALDH1A1 (0.65) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL14938480 | 0.86 | ALDH1A1 (0.65) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL2491393 | 0.82 | CYP1A2 (1.00) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL2491390 | 0.82 | CYP1A2 (1.00) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL25771679 | 0.81 | MIF (0.81) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL1563610 | 0.81 | KMT2A (0.83) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A | |
| SCHEMBL1563609 | 0.81 | KMT2A (0.83) | SMN1; SMN2RAB9ANPC1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |