Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938457 | 0.89 | ALDH1A1 (0.51) | RAD51RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14938483 | 0.86 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL14938479 | 0.83 | ALDH1A1 (0.48) | RAB9ANPC1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL14938438 | 0.75 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL14938440 | 0.75 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL14938449 | 0.74 | HSD17B10 (0.59) | RAB9ANPC1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL14938600 | 0.74 | SMN1; SMN2 (0.43) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14938727 | 0.74 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14938511 | 0.72 | ALDH1A1 (0.47) | RAD51RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14938527 | 0.72 | RAD51 (0.54) | RAD51RAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |