Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938515 | 0.82 | SMN1; SMN2 (0.47) | HSD17B10SMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL14938457 | 0.80 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1RAB9APOLBNPC1 | |
| SCHEMBL14942145 | 0.79 | RAB9A (0.52) | SMN1; SMN2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL14938435 | 0.77 | NPC1 (0.62) | SMN1; SMN2ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL14938434 | 0.77 | NPC1 (0.62) | SMN1; SMN2ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL14938727 | 0.76 | NPC1 (0.43) | SMN1; SMN2ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL14938453 | 0.76 | GAA (0.43) | SMN1; SMN2ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL14938483 | 0.76 | RAB9A (0.56) | SMN1; SMN2ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL14938600 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL14938528 | 0.74 | RAD51 (0.52) | SMN1; SMN2ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |