Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16438849 | 0.89 | ALDH1A1 (0.64) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7752872 | 0.88 | MAPT (0.78) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12186262 | 0.88 | MAPT (0.78) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27177997 | 0.88 | MAPT (0.78) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5732784 | 0.86 | RAB9A (0.81) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1563352 | 0.86 | RAB9A (0.81) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1563351 | 0.86 | RAB9A (0.81) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14938476 | 0.84 | MAPT (0.57) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| Phenyl(Methyl)Semicarbazone SCHEMBL17119918 | 0.84 | ALDH1A1 (1.00) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27532371 | 0.84 | RAB9A (0.78) | MAPTPOLBALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |