SCHEMBL7752872

SCHEMBL7752872

CC(=O)NN=C(C)c1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.78
POLB P06746 1/20 0.78
ALDH1A1 P00352 5/20 0.72
LMNA P02545 2/20 0.72
KMT2A Q03164 6/20 0.62
MEN1 O00255 5/20 0.62
NPC1 O15118 5/20 0.62
RAB9A P51151 5/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
NFKB1 P19838 2/20 0.62
NFKB2 Q00653 2/20 0.62
RELA Q04206 2/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C19 P33261 1/20 0.62
CASP3 P42574 1/20 0.62
SENP7 Q9BQF6 1/20 0.62
SENP6 Q9GZR1 1/20 0.62
ATM Q13315 1/20 0.61
METTL3 Q86U44 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27177997 1.00 MAPT (0.78) MAPTPOLBALDH1A1LMNAKMT2A
SCHEMBL12186262 1.00 MAPT (0.78) MAPTPOLBALDH1A1LMNAKMT2A
SCHEMBL14938560 0.88 MAPT (0.78) MAPTPOLBALDH1A1LMNAKMT2A
SCHEMBL5732784 0.86 RAB9A (0.81) MAPTPOLBALDH1A1LMNAKMT2A
SCHEMBL1563351 0.86 RAB9A (0.81) MAPTPOLBALDH1A1LMNAKMT2A
SCHEMBL1563352 0.86 RAB9A (0.81) MAPTPOLBALDH1A1LMNAKMT2A
SCHEMBL6638738 0.85 MAPT (0.68) MAPTPOLBALDH1A1LMNAKMT2A
SCHEMBL1562114 0.85 MAPT (0.68) MAPTPOLBALDH1A1LMNAKMT2A
SCHEMBL1562115 0.85 MAPT (0.68) MAPTPOLBALDH1A1LMNAKMT2A
Phenyl(Methyl)Semicarbazone SCHEMBL17119918 0.84 ALDH1A1 (1.00) MAPTPOLBALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580403-A2 APYRASE INHIBITORS Texas Crop Science, Inc. (US) 2025-07-09 EP claimed
US-20240101510-A1 APYRASE INHIBITORS TEXAS CROP SCIENCE, INC. 2024-03-28 US claimed
WO-2024050040-A2 APYRASE INHIBITORS TEXAS CROP SCIENCE (US) 2024-03-07 WO claimed
US-6166260-A Tandem reduction and host-guest complexation ZEELAND CHEMICALS, INC. (US) 2000-12-26 US claimed
US-20240101510-A1 APYRASE INHIBITORS TEXAS CROP SCIENCE, INC. 2024-03-28 US disclosed
EP-0858446-B1 PHENYLCARBAMATES, PROCESSES AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES BASF AG (DE) 2001-03-07 EP disclosed
US-6191284-B1 A FERROCENEYLPHOSPHINE LIGAND AND COMPLEXES USEFUL FOR HOMOGENEOUS CATALYTIC ENANTIOSELECTIVE HYDROGENATION DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) 2001-02-20 US disclosed
US-6166260-A Tandem reduction and host-guest complexation ZEELAND CHEMICALS, INC. (US) 2000-12-26 US disclosed
EP-0858446-A1 PHENYLCARBAMATES, PROCESSES AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-08-19 EP disclosed
WO-1997016415-A1 PHENYLCARBAMATES, PROCESSES AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240101510-A1 APYRASE INHIBITORS APEH, DPEP1, PON1 MAPT 4135/4885POLB 3494/4885ALDH1A1 827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.