Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939945 | 0.92 | NPSR1 (0.44) | NPSR1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL14939053 | 0.90 | NPSR1 (0.45) | NPSR1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL14939081 | 0.90 | NPSR1 (0.56) | NPSR1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL14939943 | 0.89 | NPSR1 (0.41) | NPSR1MAPTALDH1A1POLBMAPK1 | |
| SCHEMBL14939141 | 0.89 | HTR7 (0.44) | NPSR1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL14939199 | 0.89 | NPSR1 (0.55) | NPSR1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL14939610 | 0.88 | NPSR1 (0.60) | NPSR1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL14940114 | 0.87 | NPSR1 (0.41) | NPSR1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL14939295 | 0.87 | NPSR1 (0.40) | NPSR1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL14939296 | 0.86 | NPSR1 (0.50) | NPSR1MAPTALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |