Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939936 | 0.92 | NPSR1 (0.50) | NPSR1MAPTTP53LMNAKMT2A | |
| SCHEMBL14939059 | 0.90 | NPSR1 (0.51) | NPSR1MAPTTP53KMT2A | |
| SCHEMBL14938722 | 0.88 | NPSR1 (0.53) | NPSR1MAPTTP53LMNAADAM17 | |
| SCHEMBL14939733 | 0.88 | NPSR1 (0.47) | NPSR1MAPTKMT2AHTR7MAPK1 | |
| SCHEMBL14939729 | 0.87 | NPSR1 (0.68) | NPSR1MAPTLMNAADAM17 | |
| SCHEMBL14939356 | 0.85 | NPSR1 (0.58) | NPSR1MAPTTP53LMNAKMT2A | |
| SCHEMBL14939442 | 0.85 | NPSR1 (0.46) | NPSR1MAPTTP53LMNAADAM17 | |
| SCHEMBL14939710 | 0.85 | NPSR1 (0.46) | NPSR1MAPTTP53LMNAKMT2A | |
| SCHEMBL14940061 | 0.84 | NPSR1 (0.57) | NPSR1MAPTTP53LMNAKMT2A | |
| SCHEMBL14939481 | 0.84 | NPSR1 (0.46) | NPSR1MAPTTP53LMNAADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |