Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940282 | 0.93 | NPSR1 (0.51) | NPSR1MAPTLMNATP53ADAM17 | |
| SCHEMBL14939374 | 0.91 | NPSR1 (0.53) | NPSR1MAPTLMNATP53ADAM17 | |
| SCHEMBL14939726 | 0.91 | NPSR1 (0.47) | NPSR1MAPTLMNATP53ADAM17 | |
| SCHEMBL14939879 | 0.89 | NPSR1 (0.53) | NPSR1MAPTLMNATP53ADAM17 | |
| SCHEMBL14939199 | 0.88 | NPSR1 (0.55) | NPSR1MAPTLMNATP53ALDH1A1 | |
| SCHEMBL14938836 | 0.88 | NPSR1 (0.50) | NPSR1MAPTLMNATP53ADAM17 | |
| SCHEMBL14939026 | 0.87 | NPSR1 (0.47) | NPSR1MAPTLMNATP53ADAM17 | |
| SCHEMBL14939760 | 0.87 | NPSR1 (0.49) | NPSR1MAPTALDH1A1KMT2AHTR7 | |
| SCHEMBL14939602 | 0.87 | NPSR1 (0.46) | NPSR1MAPTLMNATP53ADAM17 | |
| SCHEMBL14939533 | 0.86 | NPSR1 (0.73) | NPSR1MAPTLMNAADAM17ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |