Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939786 | 0.87 | NPSR1 (0.62) | NPSR1KMT2AMAPTADAM17LMNA | |
| SCHEMBL14939710 | 0.86 | NPSR1 (0.46) | NPSR1KMT2AHTR7MAPTTP53 | |
| SCHEMBL14939843 | 0.85 | NPSR1 (0.42) | NPSR1KMT2AMAPTTP53ADAM17 | |
| SCHEMBL14938836 | 0.84 | NPSR1 (0.50) | NPSR1KMT2AHTR7MAPTTP53 | |
| SCHEMBL14939604 | 0.83 | NPSR1 (0.46) | NPSR1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14939602 | 0.83 | NPSR1 (0.46) | NPSR1KMT2AHTR7MAPTTP53 | |
| SCHEMBL14939940 | 0.82 | NPSR1 (0.47) | NPSR1KMT2AHTR7MAPTTP53 | |
| SCHEMBL14938722 | 0.82 | NPSR1 (0.53) | NPSR1KMT2AHTR7MAPTTP53 | |
| SCHEMBL14939260 | 0.82 | NPSR1 (0.49) | NPSR1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14939899 | 0.80 | NPSR1 (0.48) | NPSR1KMT2AHTR7MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |