Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939350 | 0.91 | NPSR1 (0.58) | SIGMAR1NPSR1ALDH1A1ALDH3A1KDM4E | |
| SCHEMBL14939610 | 0.89 | NPSR1 (0.60) | SIGMAR1NPSR1ALDH1A1KDM4EPOLB | |
| SCHEMBL14939592 | 0.84 | NPSR1 (0.48) | NPSR1ALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL14939141 | 0.84 | HTR7 (0.44) | NPSR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14939975 | 0.83 | NPSR1 (0.60) | SIGMAR1NPSR1ALDH1A1ALDH3A1KDM4E | |
| SCHEMBL14939022 | 0.82 | NPSR1 (0.59) | SIGMAR1NPSR1ALDH1A1ALDH3A1KDM4E | |
| SCHEMBL14939630 | 0.82 | KDM4E (0.48) | NPSR1ALDH1A1ALDH3A1KDM4EMEN1 | |
| SCHEMBL14938747 | 0.81 | NPSR1 (0.44) | NPSR1ALDH1A1ALDH3A1KDM4EPOLB | |
| SCHEMBL14939945 | 0.81 | NPSR1 (0.44) | NPSR1ALDH1A1ALDH3A1KDM4EMEN1 | |
| SCHEMBL14939943 | 0.80 | NPSR1 (0.41) | NPSR1ALDH1A1POLBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |