SCHEMBL1493916

SCHEMBL1493916

C=CC(=O)c1ccc(C#Cc2ccc(CCCCC)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 8/20 0.83
THRA P10827 7/20 0.83
MEN1 O00255 1/20 0.81
KMT2A Q03164 1/20 0.81
ATG4B Q9Y4P1 11/20 0.57
PLA2G1B P04054 9/20 0.57
CYP1A2 P05177 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
RECQL P46063 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14192330 0.90 THRB (0.81) THRBTHRAMEN1KMT2AATG4B
SCHEMBL2583757 0.90 THRB (1.00) THRBTHRAMEN1KMT2AATG4B
SCHEMBL14192575 0.89 THRB (0.65) THRBTHRAMEN1KMT2AATG4B
SCHEMBL10462600 0.87 THRB (0.91) THRBTHRAMEN1KMT2AATG4B
SCHEMBL14192407 0.87 THRB (0.91) THRBTHRAMEN1KMT2AATG4B
SCHEMBL10954360 0.86 THRB (1.00) THRBTHRAMEN1KMT2AATG4B
SCHEMBL14192426 0.86 THRB (0.74) THRBTHRAMEN1KMT2A
SCHEMBL14192418 0.86 THRB (0.74) THRBTHRAMEN1KMT2A
SCHEMBL14192545 0.86 THRB (0.61) THRBTHRAMEN1KMT2AATG4B
SCHEMBL14192343 0.86 THRB (0.64) THRBTHRAMEN1KMT2AATG4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223746-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL Zeon Corporation (JP) 2023-08-09 EP disclosed
EP-3483141-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORP (JP) 2023-07-19 EP disclosed
US-11492552-B2 Polymerizable liquid crystal material, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic body, polarizing plate, anti-reflection film, display device, and method of producing polymerizable liquid crystal composition ZEON CORPORATION (JP) 2022-11-08 US disclosed
EP-3674757-B1 POLYMERIZABLE LIQUID CRYSTAL MATERIAL, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER, OPTICAL FILM, OPTICAL ANISOTROPIC BODY, POLARIZER, ANTIREFLECTIVE FILM, DISPLAY DEVICE AND METHOD FOR MANUFACTURING POLYMERIZABLE LIQUID CRYSTAL COMPOSITION ZEON CORP (JP) 2022-04-20 EP disclosed
CN-110392703-B Polymerizable compound and method for producing same, polymerizable composition, polymer, optical film, and optically anisotropic body 日本瑞翁株式会社 2022-02-01 CN disclosed
US-11203716-B2 Compound, polymerizable compound, mixture, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic product, polarizing plate, flat panel display device, organic electroluminescence display device, and anti-reflection film ZEON CORPORATION (JP) 2021-12-21 US disclosed
CN-110003008-B Mixtures and compounds 日本瑞翁株式会社 2021-11-09 CN disclosed
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2021-08-17 US disclosed
CN-112689622-A Process for producing intermediate 日本瑞翁株式会社 2021-04-20 CN disclosed
US-10954443-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic product ZEON CORPORATION (JP) 2021-03-23 US disclosed
US-8454857-B2 Polymerizable liquid crystal compounds, polymerizable liquid crystal compositions, liquid crystalline polymers and optically anisotropic materials ZEON CORPORATION (JP) 2013-06-04 US disclosed
US-20120327318-A1 HEAT INSULATING MEMBER, HEAT INSULATING LAMINATED GLASS, AND HEAT INSULATING LAMINATED GLASS ARTICLE ZEON CORPORATION (JP) 2012-12-27 US disclosed
EP-2295477-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTAL POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS ZEON CORP (JP) 2012-11-21 EP disclosed
US-20120202084-A1 HEAT-INSULATING PARTICULATE PIGMENT AND INFRARED-REFLECTIVE COATING SOLUTION ZEON CORPORATION (JP) 2012-08-09 US disclosed
US-8158021-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optical anisotropic article ZEON CORPORATION (JP) 2012-04-17 US disclosed
US-20110140041-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS ZEON CORPORATION (JP) 2011-06-16 US disclosed
EP-2295477-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTAL POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS Zeon Corporation (JP) 2011-03-16 EP disclosed
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE ZEON CORPORATION (JP) 2010-10-14 US disclosed
EP-2143710-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICALLY ANISOTROPIC MATERIAL ZEON CORPORATION (JP) 2010-01-13 EP disclosed
US-7357964-B2 Liquid-crystalline vinyl ketone derivatives and their polymers CHISSO CORPORATION (JP) 2008-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11091452-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound PDE8A, MAPT, PLK4 THRB 4744/4885THRA 4548/4885MEN1 1191/4885
US-20110140041-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS AND OPTICALLY ANISOTROPIC MATERIALS CCNB1, CCNT1, CCNB2 THRB 4128/4885THRA 3759/4885MEN1 876/4885
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE LEO1, ZYX, CCNT1 THRB 4283/4885THRA 4059/4885MEN1 2693/4885
US-11203716-B2 Compound, polymerizable compound, mixture, polymerizable liquid crystal composition, polymer, optical film, optically anisotropic product, polarizing plate, flat panel display device, organic electroluminescence display device, and anti-reflection film NR2E3, NR3C2, NR2C2 THRB 2007/4885THRA 1913/4885MEN1 1588/4885
US-10954443-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic product NR4A1, NR2C2, NR1I3 THRB 601/4885THRA 260/4885MEN1 3068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.