Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.65 |
| ▸ | THRA | P10827 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | PLA2G1B | P04054 | 7/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192556 | 0.97 | THRB (0.61) | THRBTHRAMEN1KMT2APLA2G1B | |
| SCHEMBL14192545 | 0.92 | THRB (0.61) | THRBTHRAMEN1KMT2APLA2G1B | |
| SCHEMBL1493916 | 0.89 | THRB (0.83) | THRBTHRAMEN1KMT2APLA2G1B | |
| SCHEMBL14192505 | 0.86 | MEN1 (0.51) | THRBTHRAMEN1KMT2ATDP1 | |
| SCHEMBL14192539 | 0.84 | THRB (0.70) | THRBTHRAMEN1KMT2APLA2G1B | |
| SCHEMBL14192568 | 0.80 | THRA (0.48) | THRBTHRAMEN1KMT2ATP53 | |
| SCHEMBL14192330 | 0.79 | THRB (0.81) | THRBTHRAMEN1KMT2APLA2G1B | |
| SCHEMBL9742039 | 0.79 | HSD17B10 (0.49) | THRBKDM4EALDH1A1EGFRTP53 | |
| SCHEMBL2583757 | 0.79 | THRB (1.00) | THRBTHRAMEN1KMT2APLA2G1B | |
| SCHEMBL14192559 | 0.79 | MEN1 (0.56) | THRBTHRAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |