Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 1.00 |
| ▸ | THRA | P10827 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | ATG4B | Q9Y4P1 | 11/20 | 0.68 |
| ▸ | PLA2G1B | P04054 | 9/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192407 | 0.94 | THRB (0.91) | THRBTHRAMEN1KMT2AATG4B | |
| SCHEMBL10462600 | 0.94 | THRB (0.91) | THRBTHRAMEN1KMT2AATG4B | |
| SCHEMBL10954360 | 0.93 | THRB (1.00) | THRBTHRAMEN1KMT2AATG4B | |
| SCHEMBL1493916 | 0.90 | THRB (0.83) | THRBTHRAMEN1KMT2AATG4B | |
| SCHEMBL4904680 | 0.86 | THRB (1.00) | THRBTHRAMEN1KMT2AATG4B | |
| SCHEMBL14192353 | 0.86 | THRB (0.76) | THRBTHRAMEN1KMT2AATG4B | |
| SCHEMBL4578159 | 0.86 | THRB (0.76) | THRBTHRAMEN1KMT2AATG4B | |
| SCHEMBL14192458 | 0.85 | THRB (0.73) | THRBTHRAMEN1KMT2A | |
| SCHEMBL1482959 | 0.85 | THRA (0.73) | THRBTHRAMEN1KMT2AATG4B | |
| SCHEMBL28885266 | 0.85 | THRA (0.73) | THRBTHRAMEN1KMT2AATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| WO-2011135091-A1 | THYROID HORMONE RECEPTOR EXPRESSION FOR THE DIAGNOSIS AND PROGNOSIS ON BREAST CANCER AND OVARIAN CANCER | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-11-03 | — | — | WO | disclosed |