Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939762 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KDM4EBCHEHTTMEN1 | |
| SCHEMBL14939260 | 0.86 | NPSR1 (0.49) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL14938959 | 0.85 | NPSR1 (0.48) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL14939204 | 0.85 | KDM4E (0.44) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL14940151 | 0.84 | MEN1 (0.44) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL14939174 | 0.84 | NPSR1 (0.65) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL14939998 | 0.84 | MEN1 (0.45) | ALDH1A1KDM4EBCHEHTTMEN1 | |
| SCHEMBL14939271 | 0.83 | MEN1 (0.44) | ALDH1A1KDM4EBCHEHTTMEN1 | |
| SCHEMBL14939213 | 0.83 | MEN1 (0.44) | ALDH1A1KDM4EBCHEHTTMEN1 | |
| SCHEMBL14939831 | 0.83 | NPSR1 (0.51) | ALDH1A1KDM4EHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |