Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939765 | 0.88 | NPSR1 (0.46) | ALDH1A1KDM4ENPSR1HTR1A | |
| SCHEMBL14940084 | 0.87 | MEN1 (0.47) | MEN1KMT2AL3MBTL1BCHEALDH1A1 | |
| SCHEMBL14940355 | 0.87 | HCRTR2 (0.45) | MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL14939437 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2ABCHEALDH1A1KDM4E | |
| SCHEMBL14939887 | 0.82 | NPSR1 (0.64) | ALDH1A1KDM4EHTTNPSR1DRD2 | |
| SCHEMBL14939204 | 0.82 | KDM4E (0.44) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14940134 | 0.82 | SIGMAR1 (0.51) | MEN1KMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL14940151 | 0.81 | MEN1 (0.44) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14939174 | 0.81 | NPSR1 (0.65) | MEN1KMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL14939152 | 0.80 | KDM4E (0.44) | MEN1KMT2ABCHEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |