Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939880 | 0.93 | NPSR1 (0.52) | NPSR1MEN1KMT2ADRD2HTR2A | |
| SCHEMBL14939854 | 0.90 | CHRM2 (0.43) | LMNANPSR1KDM4EALDH1A1DRD2 | |
| SCHEMBL14939526 | 0.90 | NPSR1 (0.46) | LMNAPOLBNPSR1MEN1KMT2A | |
| SCHEMBL14938869 | 0.89 | SIGMAR1 (0.48) | NPSR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14939400 | 0.89 | NPSR1 (0.52) | LMNAPOLBNPSR1MEN1KMT2A | |
| SCHEMBL14939129 | 0.88 | NPSR1 (0.46) | LMNAPOLBNPSR1MEN1KMT2A | |
| SCHEMBL14939844 | 0.88 | NPSR1 (0.45) | LMNAPOLBNPSR1MEN1KMT2A | |
| SCHEMBL14940059 | 0.88 | NPSR1 (0.49) | NPSR1ALDH1A1MAPK1DRD2HTR2A | |
| SCHEMBL14940048 | 0.86 | ALDH1A1 (0.44) | LMNANPSR1MEN1KMT2AKDM4E | |
| SCHEMBL14939556 | 0.85 | NPSR1 (0.53) | NPSR1MEN1KMT2ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |