Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FABP6 | P51161 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939374 | 0.93 | NPSR1 (0.53) | NPSR1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL14939586 | 0.92 | NPSR1 (0.51) | NPSR1MAPTKMT2AKDM4EPHGDH | |
| SCHEMBL14940282 | 0.92 | NPSR1 (0.51) | NPSR1MAPTLMNAKMT2APHGDH | |
| SCHEMBL14939314 | 0.89 | NPSR1 (0.47) | NPSR1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL14940278 | 0.89 | NPSR1 (0.67) | NPSR1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL14939145 | 0.88 | NPSR1 (0.47) | NPSR1MAPTKMT2AKDM4EPHGDH | |
| SCHEMBL14939026 | 0.87 | NPSR1 (0.47) | NPSR1MAPTLMNAKMT2APHGDH | |
| SCHEMBL14941930 | 0.86 | NPSR1 (0.47) | NPSR1MAPTLMNAKMT2APHGDH | |
| SCHEMBL14938722 | 0.84 | NPSR1 (0.53) | NPSR1MAPTLMNAKMT2APHGDH | |
| SCHEMBL14939539 | 0.84 | NPSR1 (0.55) | NPSR1MAPTLMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |