Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939145 | 0.93 | NPSR1 (0.47) | NPSR1PHGDHMEN1KMT2AHTR1A | |
| SCHEMBL14939733 | 0.89 | NPSR1 (0.47) | NPSR1PHGDHMEN1KMT2AHTR1A | |
| SCHEMBL14938717 | 0.88 | PHGDH (0.52) | NPSR1PHGDHMEN1KMT2AHTR1A | |
| SCHEMBL14938994 | 0.88 | NPSR1 (0.47) | NPSR1MEN1KMT2AHTR1ADRD2 | |
| SCHEMBL14938722 | 0.87 | NPSR1 (0.53) | NPSR1PHGDHKMT2AALDH1A1HTT | |
| SCHEMBL14939374 | 0.87 | NPSR1 (0.53) | NPSR1PHGDHMEN1KMT2AKDM4E | |
| SCHEMBL14939174 | 0.87 | NPSR1 (0.65) | NPSR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14939609 | 0.85 | NPSR1 (0.52) | NPSR1MEN1KMT2AHTR1ADRD2 | |
| SCHEMBL14939204 | 0.85 | KDM4E (0.44) | NPSR1PHGDHMEN1KMT2AHTR1A | |
| SCHEMBL14939752 | 0.85 | MEN1 (0.55) | NPSR1MEN1KMT2AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |