Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939117 | 0.92 | NPSR1 (0.50) | NPSR1TP53MAPTLMNAKMT2A | |
| SCHEMBL14939502 | 0.91 | NPSR1 (0.52) | NPSR1TP53MAPTKMT2AMEN1 | |
| SCHEMBL14938994 | 0.90 | NPSR1 (0.47) | NPSR1MAPTLMNAKMT2ACYP2D6 | |
| SCHEMBL14938722 | 0.89 | NPSR1 (0.53) | NPSR1TP53MAPTLMNAADAM17 | |
| SCHEMBL14940280 | 0.89 | NPSR1 (0.70) | NPSR1MAPTLMNAADAM17KMT2A | |
| SCHEMBL14939026 | 0.87 | NPSR1 (0.47) | NPSR1TP53MAPTLMNAADAM17 | |
| SCHEMBL14938922 | 0.86 | NPSR1 (0.53) | NPSR1TP53MAPTLMNAADAM17 | |
| SCHEMBL14939199 | 0.86 | NPSR1 (0.55) | NPSR1TP53MAPTLMNAKMT2A | |
| SCHEMBL14939605 | 0.86 | NPSR1 (0.46) | NPSR1TP53MAPTLMNAADAM17 | |
| SCHEMBL14939244 | 0.86 | NPSR1 (0.71) | NPSR1TP53MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |