Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 4/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940422 | 0.84 | NPC1 (0.45) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14940095 | 0.84 | CYP2C9 (0.53) | NFKB1MAPTNPC1RORCHSP90AA1 | |
| SCHEMBL14940279 | 0.84 | SLC2A1 (0.48) | NFKB1KMT2AHSP90AA1APPPOLB | |
| SCHEMBL14940670 | 0.83 | KCNH3 (0.53) | RAB9A | |
| SCHEMBL4307871 | 0.78 | HSP90AA1 (0.53) | NFKB1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL49211 | 0.78 | HSP90AA1 (0.53) | MAPTMEN1KMT2AHSP90AA1SMN1; SMN2 | |
| SCHEMBL14369688 | 0.78 | CYP2C9 (0.59) | NFKB1MAPTNPC1RORCHSP90AA1 | |
| SCHEMBL8330270 | 0.77 | MAPT (0.68) | NFKB1MAPTMEN1MAPK1KMT2A | |
| SCHEMBL14940663 | 0.77 | CYP2C9 (0.53) | NFKB1MAPTMAPK1LMNANPC1 | |
| SCHEMBL16206671 | 0.77 | CYP2C9 (0.46) | MAPTMEN1KMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323488-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | UNIVERSITEIT ANTWERPEN (BE) | 2014-10-30 | — | — | US | disclosed |
| US-20140323488-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | UNIVERSITEIT ANTWERPEN (BE) | 2014-10-30 | — | — | US | disclosed |
| EP-2776410-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | Universiteit Antwerpen (BE) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013068551-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | UNIVERSITEIT ANTWERPEN (BE) | 2013-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323488-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | TBC1D15, TBC1D5, DHFR | NFKB1 559/4885MAPT 657/4885MEN1 2962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.