Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940095 | 0.88 | CYP2C9 (0.53) | SLC2A1NFKB1ABCG2HSP90AA1ADORA1 | |
| SCHEMBL14940610 | 0.87 | SLC2A1 (0.48) | SLC2A1ABCG2POLBHSP90AA1CDC7 | |
| SCHEMBL14940245 | 0.84 | NFKB1 (0.54) | NFKB1POLBKMT2AHSP90AA1APP | |
| SCHEMBL16195781 | 0.83 | SLC2A1 (0.50) | SLC2A1ABCG2CDC7ADORA1ABCC3 | |
| SCHEMBL16195734 | 0.83 | SLC2A1 (0.52) | SLC2A1ABCG2POLBCDC7SYK | |
| SCHEMBL14369688 | 0.82 | CYP2C9 (0.59) | NFKB1ABCG2HSP90AA1ADORA1ABCC3 | |
| SCHEMBL14940584 | 0.82 | HSP90AA1 (0.50) | SLC2A1NFKB1ABCG2KMT2AHSP90AA1 | |
| SCHEMBL14940663 | 0.81 | CYP2C9 (0.53) | NFKB1ABCG2POLBHSP90AA1ADORA1 | |
| SCHEMBL16206671 | 0.80 | CYP2C9 (0.46) | ABCG2KMT2AADORA1ABCC3ESR1 | |
| SCHEMBL8973372 | 0.79 | NFKB1 (0.59) | SLC2A1NFKB1ABCG2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323488-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | UNIVERSITEIT ANTWERPEN (BE) | 2014-10-30 | — | — | US | disclosed |
| US-20140323488-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | UNIVERSITEIT ANTWERPEN (BE) | 2014-10-30 | — | — | US | disclosed |
| EP-2776410-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | Universiteit Antwerpen (BE) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013068551-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | UNIVERSITEIT ANTWERPEN (BE) | 2013-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323488-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | TBC1D15, TBC1D5, DHFR | SLC2A1 1530/4885NFKB1 559/4885ABCG2 2396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.