Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27671118 | 0.85 | HCAR2 (0.71) | HCAR2LMNAALDH1A1CA12CA9 | |
| SCHEMBL337503 | 0.83 | HCAR2 (0.89) | HCAR2LMNAALDH1A1CA12CA9 | |
| SCHEMBL337504 | 0.83 | HCAR2 (0.89) | HCAR2LMNAALDH1A1CA12CA9 | |
| SCHEMBL357565 | 0.83 | HCAR2 (0.89) | HCAR2LMNAALDH1A1CA12CA9 | |
| SCHEMBL9395526 | 0.83 | HCAR2 (0.69) | HCAR2LMNAALDH1A1CA12CA9 | |
| SCHEMBL27659194 | 0.82 | HCAR2 (0.85) | HCAR2LMNAALDH1A1CA12CA9 | |
| SCHEMBL26288 | 0.82 | HCAR2 (0.67) | HCAR2LMNAALDH1A1CA12CA9 | |
| SCHEMBL9001891 | 0.81 | HCAR2 (0.61) | HCAR2LMNAALDH1A1CA12CA9 | |
| SCHEMBL11562796 | 0.81 | HCAR2 (0.61) | HCAR2LMNAALDH1A1CA12CA9 | |
| SCHEMBL219575 | 0.80 | HCAR2 (0.65) | HCAR2LMNAALDH1A1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013130684-A1 | XTEN-FOLATE CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME | AMUNIX OPERATING INC. (US) | 2013-09-06 | — | — | WO | claimed |
| CN-1343206-A | Cyclocompound | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-04-03 | — | — | CN | claimed |
| CN-108779497-A | Podocalyxin and TRA-related antibodies, methods of preparation and use as anti-cancer therapeutics | 库雷梅塔治疗有限责任公司 | 2018-11-09 | — | — | CN | disclosed |
| EP-3003387-A1 | COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES | Cytomx Therapeutics Inc. (US) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014197612-A9 | COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES | CYTOMX THERAPEUTICS, INC. (US) | 2015-03-19 | — | — | WO | disclosed |
| WO-2014197612-A1 | COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES | CYTOMX THERAPEUTICS, INC. (US) | 2014-12-11 | — | — | WO | disclosed |
| EP-2776470-A2 | ANTIBODIES SPECIFIC FOR TROP-2 AND THEIR USES | Rinat Neuroscience Corporation (US) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013068946-A2 | ANTIBODIES SPECIFIC FOR TROP-2 AND THEIR USES | RINAT NEUROSCIENCE CORP. (US) | 2013-05-16 | — | — | WO | disclosed |
| CN-101328163-A | Compounds, compositions and methods | SMITHKLINE BEECHAM CORP (US) | 2008-12-24 | — | — | CN | disclosed |
| CN-100381437-C | Compounds, compositions and methods | CYTOKINETICS INC (US) | 2008-04-16 | — | — | CN | disclosed |
| CN-1747732-A | 2-aminocarbonyl-quinoline compounds as platelet adenosine diphosphate receptor antagonists | SCHERING AG (DE) | 2006-03-15 | — | — | CN | disclosed |
| CN-1662508-A | Compounds, compositions and methods | CYTOKINETICS INC (US) | 2005-08-31 | — | — | CN | disclosed |
| CN-1489588-A | Thiazolyl-oxazolyl-pyrrolyl-and imidazolyl-acid amide derivatives useful as inbibitors of PDE 4 isozymes | �Ʒ� | 2004-04-14 | — | — | CN | disclosed |
| CN-1131216-C | Condensed 1, 2-indanes and their pharmaceutically acceptable salts, process for their preparation and their use | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-12-17 | — | — | CN | disclosed |
| CN-1343206-A | Cyclocompound | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-04-03 | — | — | CN | disclosed |
| CN-1331674-A | Sulfonamide hydroxamates | HOFFMANN LA ROCHE (CH) | 2002-01-16 | — | — | CN | disclosed |
| CN-1130903-A | Condensed 1,2-indene dihydride and its salt for medicine | TAIHO PHARMACEUTICAL CO LTD (JP) | 1996-09-11 | — | — | CN | disclosed |