Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | FABP6 | P51161 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940076 | 0.90 | NPSR1 (0.46) | NPSR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14940084 | 0.86 | MEN1 (0.47) | NPSR1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL14940355 | 0.86 | HCRTR2 (0.45) | NPSR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14939886 | 0.84 | NPSR1 (0.47) | NPSR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14939855 | 0.84 | NPSR1 (0.65) | NPSR1KMT2ARAB9ANPC1GRIN2B | |
| SCHEMBL14939589 | 0.83 | NPSR1 (0.48) | NPSR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14940304 | 0.83 | NPSR1 (0.46) | NPSR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14939131 | 0.82 | KMT2A (0.46) | NPSR1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL14939774 | 0.81 | NPSR1 (0.52) | NPSR1KMT2AMEN1RAB9ACYP2A13 | |
| SCHEMBL14938959 | 0.81 | NPSR1 (0.48) | NPSR1KMT2AMEN1RAB9ACYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |