Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939607 | 0.92 | NPSR1 (0.53) | NPSR1MAPTGAAALDH1A1MEN1 | |
| SCHEMBL14940522 | 0.92 | NPSR1 (0.53) | NPSR1TSHRMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14939113 | 0.92 | NPSR1 (0.53) | NPSR1TSHRALDH1A1MEN1MAPK1 | |
| SCHEMBL14939834 | 0.92 | NPSR1 (0.53) | NPSR1TSHRALDH1A1SIGMAR1DRD2 | |
| SCHEMBL14939434 | 0.91 | NPSR1 (0.51) | NPSR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14939051 | 0.90 | NPSR1 (0.50) | NPSR1MAPTSIGMAR1DRD2HTR2A | |
| SCHEMBL14939130 | 0.89 | NPSR1 (0.47) | NPSR1MAPTMEN1KMT2ADRD2 | |
| SCHEMBL14939846 | 0.88 | SIGMAR1 (0.52) | NPSR1TSHRMAPTGAAALDH1A1 | |
| SCHEMBL14939717 | 0.87 | NPSR1 (0.46) | NPSR1MAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14939259 | 0.86 | NPSR1 (0.65) | NPSR1TSHRMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |