Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938449 | 0.79 | HSD17B10 (0.59) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL14938515 | 0.79 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL28909466 | 0.78 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL7104950 | 0.77 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL28909447 | 0.75 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL28909455 | 0.75 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL216619 | 0.75 | HSD17B10 (0.60) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL20582046 | 0.73 | MIF (0.48) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL28909512 | 0.73 | MIF (0.48) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL14938453 | 0.73 | GAA (0.43) | SMN1; SMN2MAPTKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |