Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.34 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13032119 | 0.94 | LGALS8 (0.33) | LGALS8LGALS3EPAS1 | |
| SCHEMBL14931395 | 0.90 | LGALS8 (0.31) | LGALS8LGALS3 | |
| SCHEMBL14943011 | 0.85 | TRPV4 (0.38) | KAT6A | |
| SCHEMBL14931396 | 0.84 | — | — | |
| SCHEMBL14943084 | 0.81 | AR (0.35) | — | |
| SCHEMBL14943033 | 0.78 | — | — | |
| SCHEMBL14943035 | 0.77 | CA2 (0.32) | — | |
| SCHEMBL3483487 | 0.76 | LGALS8 (0.31) | LGALS8LGALS3 | |
| SCHEMBL14942993 | 0.74 | EPAS1 (0.31) | EPAS1 | |
| SCHEMBL3483171 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440643-B2 | Inhibitors of beta-lactamase | METHYLGENE INC. (CA) | 2013-05-14 | — | — | US | disclosed |