Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 16/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2262250 | 0.85 | EPHX2 (0.48) | PPARGEPHX2 | |
| SCHEMBL14944178 | 0.84 | EPHX2 (0.44) | PPARGEPHX2 | |
| SCHEMBL2266394 | 0.77 | MTNR1A (0.43) | PPARGEPHX2 | |
| SCHEMBL2263299 | 0.76 | CNR1 (0.42) | PPARGEPHX2 | |
| SCHEMBL12390431 | 0.76 | NPC1 (0.42) | PPARG | |
| SCHEMBL2263399 | 0.76 | PPARG (0.41) | PPARGEPHX2 | |
| SCHEMBL2263963 | 0.75 | L3MBTL1 (0.43) | PPARGEPHX2 | |
| SCHEMBL2263570 | 0.74 | TP53 (0.43) | PPARGEPHX2 | |
| SCHEMBL12390365 | 0.74 | TP53 (0.40) | — | |
| SCHEMBL2266775 | 0.73 | ALDH1A1 (0.44) | PPARGEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465869-B1 | MODULATORS OF LXR | EXELIXIS PATENT CO LLC (US) | 2013-05-15 | — | — | EP | disclosed |