Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16474688 | 0.81 | MEN1 (0.47) | MGLLPOLBL3MBTL1ALDH1A1LMNA | |
| SCHEMBL758900 | 0.81 | ALDH1A1 (0.62) | MGLLPOLBL3MBTL1ALDH1A1LMNA | |
| SCHEMBL140686 | 0.79 | ALDH1A1 (0.48) | MGLLPOLBL3MBTL1ALDH1A1LMNA | |
| SCHEMBL145883 | 0.77 | ALDH1A1 (0.50) | MGLLPOLBL3MBTL1ALDH1A1TP53 | |
| SCHEMBL12311152 | 0.77 | ALDH1A1 (0.56) | MGLLPOLBL3MBTL1ALDH1A1LMNA | |
| SCHEMBL141013 | 0.76 | CMA1 (0.44) | MGLLPOLBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL142343 | 0.76 | MGLL (0.41) | MGLLPOLBL3MBTL1ALDH1A1LMNA | |
| SCHEMBL12311153 | 0.76 | TYR (0.46) | MGLLALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL16474397 | 0.76 | ALDH1A1 (0.51) | POLBL3MBTL1ALDH1A1MAPTKDM4E | |
| SCHEMBL12311154 | 0.76 | CA1 (0.58) | POLBALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591784-A1 | Pyridine-2-one-derivatives as modulators of stress-activated protein kinase system | Intermune, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |