SCHEMBL14944447

SCHEMBL14944447

[N-]=[N+]=NCCCNCC(N)=O

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
MC4R P32245 1/20 0.33
MC3R P41968 1/20 0.33
MC1R Q01726 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16446380 0.82 LTA4H (0.33) MAOAMAOB
SCHEMBL24528646 0.77
SCHEMBL30489502 0.77 LTA4H (0.36) MAOAMAOB
SCHEMBL14090627 0.76 MC4R (0.39) MAOAMAOBMC4RMC3RMC1R
SCHEMBL21352282 0.76 CA12 (0.32)
SCHEMBL13464378 0.74
SCHEMBL19272672 0.73
SCHEMBL16006898 0.73 IDUA (0.36)
SCHEMBL7737481 0.72 MAOA (0.64) MAOAMAOB
SCHEMBL19872804 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2591795-A1 RNA targeting compounds and methods for making and using same The Research Foundation Of State University Of New York (US) 2013-05-15 EP disclosed
EP-2129388-B1 RNA TARGETING COMPOUNDS AND METHODS FOR MAKING AND USING SAME UNIV NEW YORK STATE RES FOUND 2012-09-12 EP disclosed