SCHEMBL14944711

SCHEMBL14944711

O=[N+]([O-])c1cccn1[C@H]1CC(O)[C@@H](CO)O1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 1/20 0.45
TK1 P04183 3/20 0.44
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ADRB1 P08588 1/20 0.44
DNMT1 P26358 1/20 0.44
ALOX12 P18054 1/20 0.42
ADRA1A P35348 1/20 0.42
PIM1 P11309 1/20 0.42
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
CSNK2A1 P68400 1/20 0.42
CSNK2A3 Q8NEV1 1/20 0.42
TK2 O00142 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14946761 1.00 SLC29A1 (0.45) SLC29A1TK1LMNASMN1; SMN2ADRB1
SCHEMBL2495045 1.00 SLC29A1 (0.45) SLC29A1TK1LMNASMN1; SMN2ADRB1
SCHEMBL13488842 0.82 ADK (0.35) SLC29A1TK1CYP1A2TYMSHBB
SCHEMBL2495405 0.79 TYMS (0.47) TYMS
SCHEMBL2494647 0.78 TK1 (0.51) SLC29A1TK1LMNASMN1; SMN2ADRB1
SCHEMBL13488841 0.78 TK1 (0.51) SLC29A1TK1LMNASMN1; SMN2ADRB1
SCHEMBL14946758 0.78 TK1 (0.51) SLC29A1TK1LMNASMN1; SMN2ADRB1
SCHEMBL14714996 0.78 TK1 (0.46) SLC29A1TK1LMNASMN1; SMN2ADRB1
SCHEMBL20953781 0.78 TK1 (0.51) SLC29A1TK1LMNASMN1; SMN2ADRB1
SCHEMBL14946754 0.78 TK1 (0.46) SLC29A1TK1LMNASMN1; SMN2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9285319-B2 Nucleic acid base analogs with quenching and fluorescent activities and applications thereof RIKEN (JP) 2016-03-15 US disclosed
US-20130122506-A1 NUCLEIC ACID BASE ANALOGS WITH QUENCHING AND FLUORESCENT ACTIVITIES AND APPLICATIONS THEREOF TAGCYX BIOTECHNOLOGIES C/O RIKEN (JP) 2013-05-16 US disclosed