Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TK2 | O00142 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14714996 | 1.00 | TK1 (0.46) | TK1LMNASMN1; SMN2TK2CYP1A2 | |
| SCHEMBL20953781 | 0.85 | TK1 (0.51) | TK1LMNASMN1; SMN2TK2CYP1A2 | |
| SCHEMBL14946758 | 0.85 | TK1 (0.51) | TK1LMNASMN1; SMN2TK2CYP1A2 | |
| SCHEMBL13488841 | 0.85 | TK1 (0.51) | TK1LMNASMN1; SMN2TK2CYP1A2 | |
| SCHEMBL2494647 | 0.85 | TK1 (0.51) | TK1LMNASMN1; SMN2TK2CYP1A2 | |
| SCHEMBL2498542 | 0.83 | TK1 (0.42) | TK1LMNASMN1; SMN2TK2CYP1A2 | |
| SCHEMBL14715124 | 0.78 | LMNA (0.40) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL14946761 | 0.78 | SLC29A1 (0.45) | TK1LMNASMN1; SMN2TK2CYP1A2 | |
| SCHEMBL2495045 | 0.78 | SLC29A1 (0.45) | TK1LMNASMN1; SMN2TK2CYP1A2 | |
| SCHEMBL14944711 | 0.78 | SLC29A1 (0.45) | TK1LMNASMN1; SMN2TK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130122506-A1 | NUCLEIC ACID BASE ANALOGS WITH QUENCHING AND FLUORESCENT ACTIVITIES AND APPLICATIONS THEREOF | TAGCYX BIOTECHNOLOGIES C/O RIKEN (JP) | 2013-05-16 | — | — | US | disclosed |