Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765917 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TRPA1TSHRCYP2C19L3MBTL1 | |
| SCHEMBL21765668 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TRPA1TSHRCYP2C19L3MBTL1 | |
| SCHEMBL21765664 | 0.86 | SERPINE1 (0.41) | ALDH1A1TRPA1TSHRCYP2C19ADORA1 | |
| SCHEMBL21765865 | 0.85 | CYP2C19 (0.31) | ALDH1A1TRPA1CYP2C19 | |
| SCHEMBL28196283 | 0.84 | — | — | |
| SCHEMBL21883836 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TRPA1TSHRCYP2C19L3MBTL1 | |
| SCHEMBL21765678 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TRPA1TSHRCYP2C19L3MBTL1 | |
| SCHEMBL2431445 | 0.80 | NAAA (0.50) | ALDH1A1TRPA1CYP2C19L3MBTL1NAAA | |
| SCHEMBL4954811 | 0.78 | CYP2C19 (0.53) | ALDH1A1TRPA1CYP2C19L3MBTL1NAAA | |
| SCHEMBL633774 | 0.78 | CYP2C19 (0.53) | ALDH1A1TRPA1CYP2C19L3MBTL1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |