SCHEMBL21883836

SCHEMBL21883836

O=C(CBr)OC1CCC(OC(=O)CBr)CC1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TRPA1 O75762 1/20 0.44
NAAA Q02083 2/20 0.39
CYP2C19 P33261 2/20 0.39
HTT P42858 2/20 0.37
CYP19A1 P11511 6/20 0.37
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ADORA1 P30542 1/20 0.35
SERPINE1 P05121 1/20 0.33
EPHX1 P07099 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21765678 1.00 ALDH1A1 (0.44) ALDH1A1TRPA1NAAACYP2C19HTT
SCHEMBL21765917 0.90 ALDH1A1 (0.41) ALDH1A1TRPA1NAAACYP2C19HTT
SCHEMBL21765668 0.90 ALDH1A1 (0.41) ALDH1A1TRPA1NAAACYP2C19HTT
SCHEMBL2431445 0.90 NAAA (0.50) ALDH1A1TRPA1NAAACYP2C19HTT
SCHEMBL4954811 0.88 CYP2C19 (0.53) ALDH1A1TRPA1NAAACYP2C19HTT
SCHEMBL633774 0.88 CYP2C19 (0.53) ALDH1A1TRPA1NAAACYP2C19HTT
SCHEMBL30892123 0.84 GABRA5 (0.37) ALDH1A1TRPA1NAAACYP2C19HTT
SCHEMBL8381199 0.84 KAT2B (0.35) ALDH1A1TRPA1NAAACYP2C19HTT
SCHEMBL14944752 0.84 ALDH1A1 (0.39) ALDH1A1TRPA1NAAACYP2C19ADORA1
Bromoacetic Acid SCHEMBL21811414 0.83 CYP2C19 (0.49) ALDH1A1NAAACYP2C19HTTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020054874-A1 PHOTOPOLYMERIZATION SENSITIZER 川崎化成工業株式会社 2020-03-19 WO disclosed