SCHEMBL14945114

SCHEMBL14945114

CCCCOCC(O)COCC(O)CO

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.78
HTT P42858 2/20 0.53
LPAR5 Q9H1C0 1/20 0.50
TSHR P16473 1/20 0.46
PLA2G2C Q5R387 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KDM4E B2RXH2 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SPHK1 Q9NYA1 1/20 0.44
DUSP3 P51452 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 1/20 0.41
ALOX15 P16050 1/20 0.41
CASR P41180 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
DGKA P23743 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14945115 1.00 USP2 (0.78) USP2HTTLPAR5TSHRPLA2G2C
SCHEMBL8503207 0.96 USP2 (0.84) USP2HTTLPAR5TSHRPLA2G2C
SCHEMBL8242073 0.96 USP2 (0.84) USP2HTTLPAR5TSHRPLA2G2C
SCHEMBL115795 0.96 USP2 (0.84) USP2HTTLPAR5TSHRPLA2G2C
SCHEMBL2348823 0.94 USP2 (0.74) USP2HTTLPAR5TSHRPLA2G2C
Methyl Alcohol SCHEMBL7796402 0.94 USP2 (0.81) USP2HTTLPAR5TSHRPLA2G2C
Glycerin SCHEMBL27505082 0.94 USP2 (0.81) USP2HTTLPAR5TSHRPLA2G2C
SCHEMBL14893765 0.92 USP2 (0.92) USP2HTTLPAR5PLA2G2CKDM4E
SCHEMBL9813400 0.92 USP2 (0.92) USP2HTTLPAR5PLA2G2CKDM4E
SCHEMBL9813384 0.92 USP2 (0.92) USP2HTTLPAR5PLA2G2CKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023282052-A1 CROSSLINKED ORGANIC SILICON RESIN, METHOD FOR PRODUCING SAME, AND COSMETIC 信越化学工業株式会社 2023-01-12 WO disclosed
EP-3331491-B1 POLYMERS DERIVED FROM AMINO-FUNCTIONAL VINYL ALCOHOL ETHERS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2022-03-23 EP disclosed
WO-2017189076-A1 HYDROPHILIC SILANES DOW CORNING CORPORATION (US) 2017-11-02 WO disclosed
WO-2017189077-A1 HYDROPHILIC SILANES DOW CORNING CORPORATION (US) 2017-11-02 WO disclosed
WO-2017024110-A1 POLYMERS DERIVED FROM AMINO-FUNCTIONAL VINYL ALCOHOL ETHERS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2017-02-09 WO disclosed
WO-2017024016-A1 PERSONAL CARE COMPOSITIONS COMPRISING POLYMERS DERIVED FROM VINYL ALCOHOL ETHERS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2017-02-09 WO disclosed
US-20130123530-A1 Hydrophilic Polyorganosiloxanes MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123530-A1 Hydrophilic Polyorganosiloxanes AQP1, AQP3, SGMS2 USP2 2801/4885HTT 840/4885LPAR5 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.