Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945456 | 0.80 | CYP2A6 (0.46) | CYP2A6FAAHL3MBTL1PRKCICHRNA7 | |
| SCHEMBL6947442 | 0.77 | CYP3A4 (0.47) | CYP2A6FAAHL3MBTL1CHRNA7KLKB1 | |
| Ethoxycarbonyl Group SCHEMBL27570410 | 0.75 | CYP2A6 (0.49) | CYP2A6L3MBTL1MCHR1MAPTHTR7 | |
| SCHEMBL8303438 | 0.74 | CYP2A6 (0.50) | CYP2A6FAAHL3MBTL1PRKCIMAPT | |
| SCHEMBL25185804 | 0.73 | CYP2A6 (0.49) | CYP2A6FAAHL3MBTL1PRKCIMCHR1 | |
| SCHEMBL111470 | 0.73 | CYP2A6 (0.49) | CYP2A6FAAHL3MBTL1PRKCIMCHR1 | |
| SCHEMBL14473327 | 0.73 | CYP2A6 (0.49) | CYP2A6FAAHL3MBTL1PRKCIMCHR1 | |
| SCHEMBL6583538 | 0.73 | CYP2A6 (0.49) | CYP2A6FAAHL3MBTL1PRKCICHRNA7 | |
| SCHEMBL28170416 | 0.72 | CYP2A6 (0.49) | CYP2A6FAAHL3MBTL1PRKCICHRNA7 | |
| Hydrochloric Acid SCHEMBL27898641 | 0.71 | CYP2A6 (0.47) | CYP2A6FAAHL3MBTL1PRKCICHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113564623-A | Method for preparing isatin compound by electrochemically oxidizing N-substituted indole derivative | 福建师范大学 | 2021-10-29 | — | — | CN | claimed |
| US-9944655-B2 | ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-20160297834-A1 | ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC | 2016-10-13 | — | — | US | disclosed |
| US-20150203510-A1 | ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC | 2015-07-23 | — | — | US | disclosed |
| US-8969557-B2 | ACC inhibitors and uses thereof | Nimbus Apollo, Inc. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130123231-A1 | ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203510-A1 | ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT2 | CYP2A6 1034/4885FAAH 507/4885L3MBTL1 2864/4885 |
| US-20130123231-A1 | ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT2 | CYP2A6 1034/4885FAAH 507/4885L3MBTL1 2864/4885 |
| US-20160297834-A1 | ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT2 | CYP2A6 1034/4885FAAH 507/4885L3MBTL1 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.