SCHEMBL14947865

SCHEMBL14947865

c1ccc(-n2c(-c3cc(-c4nc5cccnc5n4-c4ccccc4)nc(-c4nc5cccnc5n4-c4ccccc4)c3)nc3cccnc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50
AKT1 P31749 10/20 0.49
AKT2 P31751 4/20 0.47
AKT3 Q9Y243 2/20 0.43
PDE4B Q07343 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
PABPC1 P11940 1/20 0.42
PDE10A Q9Y233 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65343 0.91 ALDH1A1 (0.55) ALDH1A1TSHRCYP2C19AKT1AKT2
SCHEMBL13053031 0.90 ALDH1A1 (0.54) ALDH1A1TSHRCYP2C19AKT1AKT2
SCHEMBL13314063 0.88 AKT1 (0.52) ALDH1A1TSHRCYP2C19AKT1AKT2
SCHEMBL13314065 0.87 ALDH1A1 (0.49) ALDH1A1TSHRCYP2C19AKT1AKT2
SCHEMBL804897 0.86 ALDH1A1 (0.60) ALDH1A1TSHRCYP2C19AKT1AKT2
SCHEMBL8805096 0.86 ALDH1A1 (0.64) ALDH1A1TSHRCYP2C19AKT1AKT2
SCHEMBL13053034 0.86 AKT1 (0.51) ALDH1A1TSHRCYP2C19AKT1AKT2
SCHEMBL25517979 0.86 AKT1 (0.53) ALDH1A1TSHRCYP2C19AKT1AKT2
SCHEMBL13998758 0.86 AKT1 (0.53) ALDH1A1TSHRCYP2C19AKT1AKT2
SCHEMBL13314059 0.85 AKT1 (0.57) ALDH1A1TSHRCYP2C19AKT1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element UDC IRELAND LIMITED (IE) 2023-12-12 US disclosed
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element UDC IRELAND LIMITED (IE) 2023-12-12 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-20230217666-A1 Organic Electroluminescent Element And Novel Iridium Complex UDC IRELAND LTD (IE) 2023-07-06 US disclosed
US-20230217666-A1 Organic Electroluminescent Element And Novel Iridium Complex UDC IRELAND LTD (IE) 2023-07-06 US disclosed
US-20130270530-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND UDC IRELAND LIMITED (IE) 2013-10-17 US disclosed
US-20130270530-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND UDC IRELAND LIMITED (IE) 2013-10-17 US disclosed
US-20130264547-A1 MATERIALS FOR AN ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTROLUMINESCENT, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-10-10 US disclosed
US-20130264547-A1 MATERIALS FOR AN ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTROLUMINESCENT, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-10-10 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217666-A1 Organic Electroluminescent Element And Novel Iridium Complex CTCF, AP1M1, CLIC4 ALDH1A1 1521/4885TSHR 2070/4885CYP2C19 2442/4885
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element L1CAM, RER1, H1-0 ALDH1A1 203/4885TSHR 2251/4885CYP2C19 1503/4885
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element L1CAM, ZYX, H1-0 ALDH1A1 326/4885TSHR 1811/4885CYP2C19 935/4885
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device TMEM109, SLC39A11, SLC39A14 ALDH1A1 981/4885TSHR 2815/4885CYP2C19 1896/4885
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element LAS1L, CCNL2, CDC5L ALDH1A1 939/4885TSHR 4126/4885CYP2C19 2227/4885
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 ALDH1A1 981/4885TSHR 2815/4885CYP2C19 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.