SCHEMBL14947880

SCHEMBL14947880

c1ccc(-n2c(-c3cccc(-c4ccc(-c5cccc(-c6nc7cccnc7n6-c6ccccc6)c5)cc4)c3)nc3cccnc32)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 11/20 0.54
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
CYP2C19 P33261 1/20 0.52
AKT2 P31751 5/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
HSP90AA1 P07900 1/20 0.46
AKT3 Q9Y243 3/20 0.43
PDE4B Q07343 2/20 0.43
POLB P06746 1/20 0.41
PABPC1 P11940 1/20 0.41
GAA P10253 1/20 0.41
PI4KA P42356 1/20 0.41
PI4K2B Q8TCG2 1/20 0.41
PI4K2A Q9BTU6 1/20 0.41
PI4KB Q9UBF8 1/20 0.41
PDE4D Q08499 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16201587 0.97 AKT1 (0.56) AKT1ALDH1A1TSHRCYP2C19AKT2
SCHEMBL13314059 0.96 AKT1 (0.57) AKT1ALDH1A1TSHRCYP2C19AKT2
SCHEMBL14947873 0.92 AKT1 (0.51) AKT1ALDH1A1TSHRCYP2C19AKT2
SCHEMBL13998723 0.92 AKT1 (0.56) AKT1ALDH1A1TSHRCYP2C19AKT2
SCHEMBL14582732 0.92 ALDH1A1 (0.55) AKT1ALDH1A1TSHRCYP2C19AKT2
SCHEMBL18082488 0.91 AKT1 (0.47) AKT1ALDH1A1TSHRCYP2C19AKT2
SCHEMBL65343 0.90 ALDH1A1 (0.55) AKT1ALDH1A1TSHRCYP2C19AKT2
SCHEMBL13916708 0.90 ALDH1A1 (0.58) AKT1ALDH1A1TSHRCYP2C19AKT2
SCHEMBL16139466 0.89 ALDH1A1 (0.46) AKT1ALDH1A1TSHRCYP2C19AKT2
SCHEMBL12853966 0.89 AKT1 (0.52) AKT1ALDH1A1TSHRCYP2C19AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-20220336752-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element UDC IRELAND LIMITED (IE) 2022-10-20 US disclosed
US-20210249611-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LTD (IE) 2021-08-12 US disclosed
US-11038122-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2021-06-15 US disclosed
US-10720586-B2 Organic electroluminescent device; a charge transporting material for the organic electroluminescent device; and a luminescent device, a display device and a lighting system using the organic electroluminescent device UDC IRELAND LIMITED (IE) 2020-07-21 US disclosed
US-20140291652-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING DEVICE, DISPLAY DEVICE, AND ILLUMINATION DEVICE USING SAID ELEMENT UDC IRELAND LIMITED (IE) 2014-10-02 US disclosed
US-20140034914-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LIMITED (IE) 2014-02-06 US disclosed
US-20140034914-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LIMITED (IE) 2014-02-06 US disclosed
US-20130264547-A1 MATERIALS FOR AN ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTROLUMINESCENT, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-10-10 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220336752-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element L1CAM, NR2E3, OR10J3 AKT1 1358/4885ALDH1A1 224/4885TSHR 2806/4885
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element L1CAM, RER1, H1-0 AKT1 2025/4885ALDH1A1 203/4885TSHR 2251/4885
US-11038122-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device TMEM109, SLC39A11, SLC39A14 AKT1 3156/4885ALDH1A1 981/4885TSHR 2815/4885
US-20210249611-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 AKT1 3156/4885ALDH1A1 981/4885TSHR 2815/4885
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element L1CAM, ZYX, H1-0 AKT1 2027/4885ALDH1A1 326/4885TSHR 1811/4885
US-10720586-B2 Organic electroluminescent device; a charge transporting material for the organic electroluminescent device; and a luminescent device, a display device and a lighting system using the organic electroluminescent device L1CAM, SLC19A2, RPS19 AKT1 3132/4885ALDH1A1 25/4885TSHR 1847/4885
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device TMEM109, SLC39A11, SLC39A14 AKT1 3156/4885ALDH1A1 981/4885TSHR 2815/4885
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 AKT1 3156/4885ALDH1A1 981/4885TSHR 2815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.