Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612194 | 0.93 | KIF11 (0.49) | KIF11SIRT2CNR2PSMD14ALDH1A1 | |
| SCHEMBL825812 | 0.81 | KIF11 (0.67) | KIF11 | |
| SCHEMBL14962369 | 0.72 | KIF11 (0.74) | KIF11 | |
| SCHEMBL12551466 | 0.72 | ALDH1A1 (0.45) | CNR2PSMD14ALDH1A1CYP3A4TSHR | |
| SCHEMBL12342194 | 0.71 | CNR2 (0.53) | CNR2PSMD14ALDH1A1CYP3A4TSHR | |
| SCHEMBL3490247 | 0.71 | CNR2 (0.53) | CNR2PSMD14ALDH1A1CYP3A4TSHR | |
| SCHEMBL3490254 | 0.71 | CNR2 (0.53) | CNR2PSMD14ALDH1A1CYP3A4TSHR | |
| SCHEMBL14137955 | 0.71 | SLC2A1 (0.53) | CNR2PSMD14ALDH1A1CYP3A4TSHR | |
| SCHEMBL10942182 | 0.70 | CNR2 (0.52) | CNR2PSMD14ALDH1A1CYP3A4TSHR | |
| SCHEMBL443135 | 0.69 | SLC2A1 (0.42) | ALDH1A1CYP3A4TSHRMAPK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130122516-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MEDICAL SYSTEMS, INC. | 2013-05-16 | — | — | US | disclosed |
| US-20130122516-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MEDICAL SYSTEMS, INC. | 2013-05-16 | — | — | US | disclosed |