SCHEMBL14948261

SCHEMBL14948261

c1ccc(-n2c3ccccc3c3cc(-c4cccc([Si](c5ccccc5)(c5ccccc5)c5ccc6c7ccccc7c7ccccc7c6c5)c4)ccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
PTGER4 P35408 1/20 0.35
KMT2A Q03164 2/20 0.34
IL1R1 P14778 1/20 0.34
TSPO P30536 2/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
NPY5R Q15761 1/20 0.32
DNM1 Q05193 1/20 0.32
HDAC4 P56524 1/20 0.32
RXFP1 Q9HBX9 1/20 0.31
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31
RAC1 P63000 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948268 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL14948260 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17463258 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL14948262 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17461065 0.94 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17463316 0.94 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17461144 0.94 L3MBTL1 (0.49) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL20988747 0.94 L3MBTL1 (0.49) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL23156450 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17481833 0.92 L3MBTL1 (0.50) L3MBTL1KDM4EATMPTGER4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160028030-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2016-01-28 US disclosed
US-20160028030-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2016-01-28 US disclosed
EP-2977378-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd (KR) 2016-01-27 EP disclosed
US-9142788-B2 Host materials for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2015-09-22 US disclosed
US-9142788-B2 Host materials for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2015-09-22 US disclosed
US-8652656-B2 Triphenylene silane hosts UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 US disclosed
US-8652656-B2 Triphenylene silane hosts UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 US disclosed
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS UNIVERSAL DISPLAY CORPORATION (US) 2013-05-16 US disclosed
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS UNIVERSAL DISPLAY CORPORATION (US) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS OCIAD2, OCIAD1, YAP1 L3MBTL1 659/4885KDM4E 3627/4885ATM 2752/4885
US-20160028030-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CCNE1 L3MBTL1 863/4885KDM4E 1882/4885ATM 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.