SCHEMBL14948418

SCHEMBL14948418

CC[PH](CC)(CC)Cc1cccc(N(c2ccc(I)c(C[PH](CC)(CC)CC)c2)c2ccc(I)c(C[PH](CC)(CC)CC)c2)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948367 0.84 S1PR1 (0.33)
SCHEMBL596875 0.70 TP53 (0.38)
SCHEMBL14948362 0.70 CYP2C19 (0.33)
SCHEMBL76603 0.66 TP53 (0.52) SIGMAR1
SCHEMBL13136839 0.66 TP53 (0.52) SIGMAR1
SCHEMBL8765716 0.65 SIGMAR1 (0.47) SIGMAR1
SCHEMBL8766587 0.64 TP53 (0.44) SIGMAR1
SCHEMBL17678530 0.64 BCL2 (0.46) SIGMAR1
SCHEMBL14948363 0.64 CYP2C19 (0.42) SIGMAR1
SCHEMBL12957222 0.63 TP53 (0.54) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed