SCHEMBL14948447

SCHEMBL14948447

Cc1ccc(N(c2ccccc2)c2ccc(C)c(CCl)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.39
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 3/20 0.34
NPSR1 Q6W5P4 2/20 0.34
TACR1 P25103 1/20 0.34
APP P05067 1/20 0.33
NPC1 O15118 4/20 0.33
RAB9A P51151 4/20 0.33
MEN1 O00255 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
JAK2 O60674 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16574302 0.81 L3MBTL1 (0.39) CYP2C19ALDH1A1MAPTTDP1KDM4E
SCHEMBL13699887 0.81 ALDH1A1 (0.42) CYP2C19ALDH1A1MAPTTDP1KDM4E
SCHEMBL14948342 0.80 CYP2C19 (0.36) CYP2C19ALDH1A1MAPTTDP1KDM4E
SCHEMBL14981536 0.80 S1PR1 (0.40) ALDH1A1MAPTTAAR1HPGDSMN1; SMN2
SCHEMBL2308261 0.79 ALDH1A1 (0.43) CYP2C19ALDH1A1MAPTTDP1KDM4E
SCHEMBL19320270 0.79 TAAR1 (0.38) CYP2C19ALDH1A1MAPTTDP1KMT2A
SCHEMBL14981535 0.79 TAAR1 (0.38) CYP2C19ALDH1A1MAPTTDP1KMT2A
SCHEMBL2744087 0.77 ALDH1A1 (0.48) CYP2C19ALDH1A1MAPTTDP1KDM4E
SCHEMBL14163842 0.77 ALDH1A1 (0.48) CYP2C19ALDH1A1MAPTTDP1KDM4E
SCHEMBL14163845 0.77 ALDH1A1 (0.48) CYP2C19ALDH1A1MAPTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed