SCHEMBL14948652

SCHEMBL14948652

Cc1ccc(/C=C(/C(=O)O)C(F)(F)F)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.43
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
FOS P01100 1/20 0.40
JUN P05412 1/20 0.40
MAPT P10636 4/20 0.39
RAB9A P51151 2/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
CYP2A6 P11509 1/20 0.39
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
CA2 P00918 1/20 0.38
KMT2A Q03164 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564118 0.82 AKR1C3 (0.50) AKR1C3CES1CYP1A1CYP1B1MAPT
SCHEMBL8054477 0.82 AKR1C3 (0.50) AKR1C3CES1CYP1A1CYP1B1MAPT
SCHEMBL7146881 0.82 AKR1C3 (0.50) AKR1C3CES1CYP1A1CYP1B1MAPT
SCHEMBL22123624 0.81 ALDH1A1 (0.50) AKR1C3MAPTALDH1A1KMT2ASMN1; SMN2
SCHEMBL14948651 0.81 TPMT (0.33) CES2CES1
Hydrochloric Acid SCHEMBL6510831 0.81 AKR1C3 (0.48) AKR1C3CES1CYP1A1CYP1B1MAPT
SCHEMBL14948653 0.75 RAB9A (0.37) CES2CES1MAPTRAB9ANPC1
SCHEMBL7071418 0.75 AKR1C3 (0.46) AKR1C3FOSJUNMAPTRAB9A
SCHEMBL7071420 0.75 AKR1C3 (0.46) AKR1C3FOSJUNMAPTRAB9A
SCHEMBL6673168 0.74 AKR1C3 (0.49) AKR1C3FOSJUNMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2776515-B1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2019-08-28 EP disclosed
US-9171676-B2 Organic colourant and uses thereof in photovoltaic cells COMMISSARIAT {dot over (A)} L'ĖNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (FR) 2015-10-27 US disclosed
US-20140290748-A1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-10-02 US disclosed
WO-2013068588-A1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2013-05-16 WO disclosed