SCHEMBL14948653

SCHEMBL14948653

Cc1ccc(/C=C(/C(=O)O)C(F)(F)F)nc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 6/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
HPGD P15428 1/20 0.34
CCR1 P32246 1/20 0.33
CCR5 P51681 1/20 0.33
CCR8 P51685 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPC1 O15118 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TP53 P04637 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26932629 0.79 RAB9A (0.40) RAB9AMAPTKDM4EL3MBTL1CCR1
SCHEMBL26932950 0.79 RAB9A (0.40) RAB9AMAPTKDM4EL3MBTL1CCR1
SCHEMBL16141474 0.77 AKR1C3 (0.44) RAB9AMAPTKDM4EL3MBTL1CCR1
SCHEMBL14948652 0.75 AKR1C3 (0.43) RAB9AMAPTCES2CES1HPGD
SCHEMBL21726046 0.73 RAB9A (0.38) RAB9AMAPTKDM4EL3MBTL1CCR1
SCHEMBL14948650 0.72 EGFR (0.45) KDM4EHPGDKMT2AALDH1A1
SCHEMBL22319799 0.71 ALDH1A1 (0.47) RAB9AMAPTKDM4EL3MBTL1HPGD
SCHEMBL31540750 0.70 KDM4E (0.38) RAB9AMAPTKDM4EL3MBTL1CCR1
SCHEMBL14042504 0.70 CCR1 (0.44) RAB9AMAPTKDM4EL3MBTL1CCR1
SCHEMBL1124264 0.69 KDM4E (0.46) RAB9AMAPTKDM4EHPGDCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2776515-B1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2019-08-28 EP disclosed
US-9171676-B2 Organic colourant and uses thereof in photovoltaic cells COMMISSARIAT {dot over (A)} L'ĖNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (FR) 2015-10-27 US disclosed
US-20140290748-A1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-10-02 US disclosed
WO-2013068588-A1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2013-05-16 WO disclosed