Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116437 | 0.88 | PTGS2 (0.66) | PTGS2MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL6539438 | 0.84 | KMT2A (0.51) | MEN1KMT2APKMRECQLALDH1A1 | |
| SCHEMBL4427417 | 0.83 | PKM (0.54) | MEN1KMT2APKMRECQLALDH1A1 | |
| SCHEMBL171840 | 0.83 | MEN1 (0.61) | MEN1KMT2APKMRECQLALDH1A1 | |
| SCHEMBL17775464 | 0.83 | ALOX15 (0.59) | MEN1KMT2APKMRECQLALDH1A1 | |
| SCHEMBL13916156 | 0.83 | KMT2A (0.54) | MEN1KMT2APKMRECQLALDH1A1 | |
| SCHEMBL10119179 | 0.83 | PTGS2 (0.57) | PTGS2MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL12061812 | 0.82 | GAA (0.66) | PTGS2MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL17365269 | 0.82 | PTGS2 (0.60) | PTGS2MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL778673 | 0.81 | MEN1 (0.52) | MEN1KMT2APKMRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637658-B2 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130123475-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | Life Technologies Corporation (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123475-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | DNTT, PNP, NT5C2 | PTGS2 4417/4885MEN1 3897/4885KMT2A 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.