SCHEMBL14949281

SCHEMBL14949281

COCc1cc(CO)cc(COC)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.48
MAPT P10636 2/20 0.41
PRKCE Q02156 2/20 0.35
MYLK Q15746 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
PRKCG P05129 1/20 0.35
PRKCA P17252 1/20 0.35
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
DAO P14920 1/20 0.34
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14949268 0.93 ACHE (0.42) ACHEMAPTPRKCEMYLKTDP1
SCHEMBL23734489 0.93 ACHE (0.61) ACHEMAPTPRKCEMYLKTDP1
SCHEMBL19142118 0.91 ACHE (0.41) ACHEMAPTPRKCEMYLKTDP1
SCHEMBL2904830 0.91 ACHE (0.41) ACHEMAPTPRKCEMYLKTDP1
SCHEMBL19532627 0.89 ACHE (0.39) ACHEMAPTPRKCEMYLKTDP1
SCHEMBL1620230 0.89 GRIN2D (0.47) ACHEMAPTALDH1A1CYP4F2CYP4A11
SCHEMBL18553335 0.89 ACHE (0.39) ACHEMAPTPRKCEMYLKTDP1
SCHEMBL3624689 0.86 PRKCE (0.37) MAPTPRKCEMYLKTDP1MEN1
SCHEMBL23656263 0.85 LMNA (0.39) ACHEMAPTTDP1MEN1ALDH1A1
SCHEMBL25370004 0.84 ACHE (0.35) ACHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013069812-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM, MASK BLANK AND METHOD OF FORMING PATTERN FUJIFILM CORPORATION (JP) 2013-05-16 WO disclosed