Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957150 | 0.77 | KDM4E (0.36) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL32690599 | 0.76 | KDM4E (0.39) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14949533 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL13448704 | 0.75 | ALDH1A1 (0.40) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4928521 | 0.74 | KDM4E (0.38) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2847319 | 0.72 | KDM4E (0.41) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9506471 | 0.72 | KDM4E (0.39) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21393151 | 0.71 | TSHR (0.33) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30389190 | 0.71 | SPHK1 (0.37) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18122821 | 0.70 | KDM4E (0.63) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445501-B2 | Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines | TAKEDA GMBH (DE) | 2013-05-21 | — | — | US | disclosed |