Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595642 | 0.82 | ALDH1A1 (0.36) | TSHRALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL10593961 | 0.82 | ALDH1A1 (0.36) | TSHRALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL8762317 | 0.80 | ALDH1A1 (0.36) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL9641206 | 0.76 | TSHR (0.35) | TSHRALDH1A1FGFR4MAPK1TDP1 | |
| SCHEMBL1957150 | 0.75 | KDM4E (0.36) | TSHRP2RX7KDM4EKMT2AALDH1A1 | |
| SCHEMBL7751502 | 0.75 | TSHR (0.38) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL32690599 | 0.74 | KDM4E (0.39) | TSHRP2RX7KDM4EKMT2AALDH1A1 | |
| SCHEMBL3887596 | 0.74 | TSHR (0.37) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL13448704 | 0.74 | ALDH1A1 (0.40) | P2RX7KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3592430 | 0.73 | TACR2 (0.31) | TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190293641-A1 | ASSAY | IMPERIAL COLLEGE INNOVATIONS, LTD. (GB) | 2019-09-26 | — | — | US | disclosed |